Oregon has roughly 30 licensed psilocybin service centers operating under Measure 109. Colorado issued its first Regulated Natural Medicine license in 2026. New Mexico's Medical Psilocybin Program launches Q4 2026. Massachusetts Question 4 is advancing. Card networks treat any psilocybin MID reference as a controlled-substance violation regardless of state law. Clay Pay places these files at acquirers willing to underwrite state-legal service providers, with the compliance package (state license, facilitator credentials, HIPAA workflow, patient intake protocol) packaged for the sponsoring bank.